Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor used in the procedure of several myeloma. Its synthesis or research is vital for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers such as breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is essential for optimizing the output approach and ensuring superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is utilised to take care of breast cancer, and these intermediates are associated with its creation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast cancer. Many intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers like ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-4 to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked CAS NO.132127-34-5 to the synthesis of assorted gluconic acid derivatives, which happen to be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a 16-dien-3-ol medication applied to control form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).